Calming tablets Adaptol - negative reviews. Neutral. Positive. + Leave a review Negative reviews Anna Appointed by a neurologist, did NOT help and greatly worsened the situation, became more divisive

A huge number of people suffer from vegetative-vascular dystonia nowadays. VSD is not a disease, it is a complex of psychosomatic symptoms. But they can greatly worsen a person’s condition and quality of life. Many people are prescribed Adaptol for VSD and panic attacks. How to take this medicine, what its effect is and whether it helps with neuroses, dystonia, panic attacks - these are the questions we will consider in the article. Do not forget that despite the available information, any medicine must be prescribed by a doctor. This material is presented for informational purposes only.

Composition and properties of Adaptol

One capsule contains:

• active substance - mebicar 300 mg;
• excipients: methyl cellulose, calcium stearate;
• composition of the capsule body and lid: gelatin, titanium dioxide E171.

Description: hard gelatin capsules No. 0 white/white, containing white or almost white powder, are allowed in the form of a compacted column that crumbles when touched by a glass rod. Heterogeneity in particle size is allowed.

Pharmacotherapeutic group: Psychotropic drugs. Anxiolytics. Other anxiolytics.

ATX code: N05BX

Compound

The drug contains the main active ingredient, as well as a number of auxiliary compounds. The active ingredient of adaptol in tablets and capsules is mebicar. The amount in each tablet or capsule corresponds to the dosage of the medication indicated on the package.

Excipients of the product in capsule form are calcium and titanium compounds, cellulose and gelatin. The tablets contain excipients such as calcium stearate and methylcellulose. Only the active substance has an effect on the body. The remaining components have a very low concentration and do not affect health. They are necessary in order to form a capsule or tablet.

Pharmacological properties

Pharmacokinetics

When the drug is administered orally, 77-80% of the taken dose of mebicar enters the blood, up to 40% of which is bound by erythrocytes.

The rest of the active substance does not bind to blood plasma proteins and is found in the plasma in a free form, therefore it is freely distributed throughout the body and freely overcomes cell membranes.

The maximum concentration of mebicar in the blood is reached after 0.5 hours, and the high level remains for 3-4 hours, then gradually decreases.

The half-life is 8 hours.

Mebicar is completely excreted from the body in urine and feces within 24 hours.

The drug does not undergo biochemical transformations and does not accumulate in the body.

Pharmacodynamics

Adaptol has moderate tranquilizing activity, eliminates or weakens restlessness, anxiety, fear, internal emotional tension and irritability.

Adaptol acts on the activity of structures included in the limbic-reticular complex, in particular, on the emotiogenic zones of the hypothalamus, and also has an effect on all 4 main neurotransmitter systems - GABA, choline, serotonin and adrenergic, promoting their balance and integration, but not has a peripheral adrenergic effect.

The tranquilizing effect of the drug is not accompanied by muscle relaxation and impaired coordination of movements. On this basis, Adaptol® is called a “daytime tranquilizer.”

It does not have a hypnotic effect, but enhances the effect of sleeping pills and improves sleep in case of sleep disturbances.

Adaptol eases or relieves nicotine withdrawal.

Pharmacological action of Adaptol

The drug belongs to the group of anxiolytic drugs. The active substance has identical properties, similar to natural metabolites produced by the human body. The product has an identical structure to some components of urea.

The medication has a stimulating effect on systems related to limbic and reticular functions, having a direct effect on the hypothalamus and its zones. In this case, there is an effect on the emotional parts of the hypothalamus and neurotransmitters. However, the drug does not have an adrenergic blocking effect.

The components of the medicine help eliminate anxiety, worry and fear, reducing psycho-emotional stress and irritability. At the same time, the metabolites are not addictive and do not interfere with basic psychomotor functions, including coordination of movement and reactions.

The drug does not have a negative effect on mental and intellectual processes and does not reduce the body’s motor ability. There is an absence of any euphoric states when using the product.

The medication does not have a pronounced sedative effect, but has a direct effect on drugs that have a hypnotic effect. In connection with this. It is often used as part of complex therapy for any sleep disorders.

Application of Adaptol (method, dosage)

Adult patients take Adaptol orally, regardless of meals, 300-600 mg 2-3 times a day.

The maximum single dose is 3 g, the daily dose is 10 g.

The duration of treatment ranges from several days to 2-3 months.

In complex therapy, as a means of reducing the desire to smoke tobacco, the drug is prescribed at a dose of 600-900 mg 3 times a day for 5-6 weeks.

Elderly patients do not need dose selection.

Patients with liver failure do not need to reduce the dose.

in patients with renal failure . This group of patients should use the drug with caution.

Addiction, addiction and withdrawal syndrome to Adaptol® have not been established.

If the next dose has not been taken, continue the course of treatment at the previously prescribed doses. If necessary, you should consult your doctor.

Adaptol - indications

The drug Adaptol is prescribed to patients suffering from various types of neurotic disorders.

The main indications include:

• Neuroses of varying severity.
• Vegetative-vascular dystonia.
• Panic attacks.
• Mild degree of depression.
• Oxidative stress of various origins. Increased anxiety and irritability.
• PMS and menopausal syndrome in women.
• Angina pectoris of a psychosomatic nature (pain in the heart).
• Rehabilitation period after myocardial infarction.
• As part of complex therapy in the treatment of alcoholism, hangover syndrome and nicotine addiction.
• Reducing the side effects of antipsychotics.

Side effects

Adaptol, like other medicines, can cause side effects that may not affect all patients. Adaptol is usually well tolerated.

Classification of undesirable side reactions by frequency of development: very often (≥ 1/10); often (≥ 1/100 to < 1/10); uncommon (≥ 1/1000 to < 1/100); rare (≥ 1/10,000 to < 1/1000); very rare (<1/10,000); frequency of manifestation is unknown (cannot be determined from available data)*.

Rarely:

• dizziness;
• arterial hypotension;
• dyspeptic disorders (heartburn, belching, feeling of fullness in the abdomen, diarrhea);
• allergic reactions (itching of the skin) are possible;
• decreased body temperature;
• weakness.

In case of an allergic reaction, you should stop taking the drug.

Some data on acute hypersensitivity reactions have been obtained.

Indications for use of Adaptol

Prescribed in therapy:

• neuroses;
• neurosis-like conditions;
• emotional instability, accompanied by irritation, anxiety, and an unreasonable feeling of fear;
• cardialgia not associated with coronary heart disease;
• manifestations of a somatovegetative nature;
• severe stressful conditions;
• nicotine addiction (helps reduce the craving for smoking).

It is also used for long-term treatment with neuroleptics, tranquilizers, it makes it easier to tolerate heavy drugs, and significantly reduces the occurrence of adverse reactions.

Prescribed to women during menopause, as well as with pronounced premenstrual syndrome, it helps reduce the severity of somatovegetative symptoms.

Indications for the use of Adaptol are:

• Neuroses and neurosis-like symptoms (irritability, emotional instability, anxiety, fear);
• Cardialgia of various origins (not associated with coronary heart disease);
• Oxidative stress of various etiologies (as an adaptogen and cerebroprotector);
• Nicotine withdrawal (as part of complex treatment to reduce the desire to smoke);
• Severe vegetative manifestations during PMS and menopause in women;
• Poisoning or adverse reactions to benzodiazepines;
• Poisoning or adverse reactions to neuroleptic and antipsychotic drugs.

Hypersensitivity to tetramethyltetraazabicyclooctanedione. Adaptol, according to the instructions, is contraindicated in children under 10 years of age.

special instructions

In cases of hypotension and/or decreased body temperature (body temperature may drop by 1-1.5 °C), discontinuation of the drug is not required.

Blood pressure and body temperature normalize on their own within a few days.

Features of the effect of the drug on the ability to drive a vehicle or potentially dangerous mechanisms

Should not be used during work by vehicle drivers and people whose profession involves increased concentration of attention.

Overdose

The exact doses that can lead to an overdose of the drug are unknown. If you take a large number of tablets or capsules, you may develop conditions corresponding to side effects. Increasing the dose increases the risk of allergic reactions, including bronchospasm. In addition, the probability of developing pathology of the digestive system is dose-dependent.

If an overdose is suspected, it is necessary to carry out a set of detoxification measures. First of all, rinse the victim’s stomach and give a siphon enema. In severe cases, the patient is hospitalized in the intensive care unit, where infusion therapy is performed.

Packaging, storage and manufacturer

Information from the packaging of Adaptol capsules 300 mg

Analogs

Drugs included in the same pharmacological group with Adaptol include:

• Atarax;
• Afobazole;
• Diazepam;
• Zolomax;
• Xanax;
• Relanium.

The following have identical active ingredients:

• Mebicar IC;
• Mebikar Tathimpharm;
• Tranquilar IC.

In the same anatomical-therapeutic-chemical group as Adaptol are:

• Alprazolam;
• Amizil;
• Gidazepam;
• Grandaxin;
• Sibazon;
• Elenium.

Russian analogues of Adaptol are less expensive than the original, but it is important to remember that replacing one drug with another can only be done with the permission of the attending physician.

To understand what is better – the original or cheaper substitutes, it is recommended that you read the brief information about the drugs:

1. Phenibut. Phenibut is a nootropic drug with a pronounced antipsychotic effect.

Has a wide range of applications:

• anxious, neurasthenic states;
• neurosis;
• unreasonable feeling of fear;
• psychopathic disorders;
• enuresis;
• myelodysplasia;
• depression;
• relief of withdrawal symptoms in patients during treatment for alcoholism;
• psycho-emotional and mental stress;
• insomnia, frequent awakenings at night, nightmares.

It can also be prescribed to patients before surgical interventions and other medical procedures that cause the patient a feeling of anxiety and fear.

The average cost for 10 tablets is 65 rubles.

Like the original, it is impossible to buy Phenibut tablets without prescriptions in Moscow and other Russian cities.

Neurologists consider both drugs to be of very high quality and powerful. The main differences between the original and the analogue are in the composition, cost and the prohibition of taking Phenibut for patients with severe damage to the liver, kidneys, or stomach ulcers.

1. Afobazol. Another Russian analogue, which has similar indications for use, but is cheaper in cost (60 tablets can be purchased for about 360 rubles).

Can be prescribed in complex therapy for patients with somatic, dermatological, and oncological diseases. Effective in facilitating the period of quitting smoking.

When choosing between the drugs Adaptol or Afobazole for the treatment of severe psychological problems, experts give preference to the first. Afobazole is a more gentle anxiolytic.

Adaptol tablets are a true help for those whose health has been affected by mental pathologies. Shows high positive results and is trusted by doctors.

Not suitable as a means for self-medication, requires therapy under the supervision of a specialist.