Interaction of Phenibut with drugs - consequences of taking


Release form and composition

The drug is based on aminophenylbutyric acid (acidum aminophenylbutyricum in Latin). The following substances are used as auxiliary components:

  • microcrystalline cellulose;
  • calcium stearate;
  • sodium starch glycolate;
  • colloidal silicon dioxide.

Available in the form of flat-cylindrical tablets of white or cream color. Surface with chamfer and notch. One unit contains 250 mg of the main substance (phenibut). Packaged in cardboard packages of 1 or 2 blisters, respectively, 10 or 20 pieces. Blisters are equipped with contour cells. If necessary, you can purchase Phenibut in powder form. To do this, you need to leave an order at the pharmacy.

pharmachologic effect

The drug is a derivative of phenylethylamine and gamma-aminobutyric acid (GABA) of the phenyl type, due to which it reduces the level of tension, fear, anxiety, has an anxiolytic effect, and relieves insomnia. When taken simultaneously with sleeping pills, neuroleptics and narcotic drugs, the effect of the latter is enhanced.

What is Phenibut?

Phenibut is a nootropic psychostimulant that inhibits neurotransmitters of the central nervous system. The active substance has a crystalline structure and a sour taste. To make tablets, a white powdery mass is used, soluble in alcohol and water. pH values ​​in an aqueous solution correspond to the norm of 2.3-2.7.

Pharmacodynamics

The nootropic affects the integrative higher functionality of the brain, stimulating mental activity, memory and other abilities. Increases brain stability under increased loads, stressful situations and hypoxia (oxygen starvation). Has the following effect on the body:

  1. Strengthens cortico-subcortical connections (elements connecting the cortex with the subcortical sections).
  2. Normalizes tissue metabolism, accelerates blood supply, which improves brain functionality.
  3. Reduces blood vessel resistance.
  4. Has antiplatelet properties.
  5. Has an anticonvulsant effect.
  6. Increases the latent period. This reduces nystagmus.
  7. Reduces asthenia, relieves vasovegetative symptoms.
  8. Reduces the excitability of subcortical elements, thalamus, hypothalamus, limbic complex.
  9. Accelerates the transmission of nerve impulses.
  10. Delays induced and spontaneous platelet aggregation, thereby preventing the development of thrombosis.
  11. Increases the number of mitochondria in the affected area during traumatic brain injury, where perifocal changes occur.
  12. Utilizes excess glucose.
  13. Launches energy processes.
  14. Improves tissue respiration.

Achieved effect:

  • the accuracy of the sensory-motor reaction is stabilized;
  • memory is restored;
  • concentration improves;
  • mental capacity increases;
  • performance increases during the daytime;
  • insomnia disappears at night;
  • anxiety and restlessness are reduced;
  • pain in the head and feeling of heaviness are relieved;
  • irritability disappears (sedative effect);
  • emotional lability increases;
  • clarity of consciousness appears.

The drug does not have a negative effect on adrenergic and cholinergic receptors, does not depress the central nervous system, does not relax muscles, and therefore can be used even in old age. Positive dynamics are observed after long-term use, as the effect develops gradually.

Pharmacokinetics

After penetration into the body, the active substance is quickly absorbed, evenly distributed throughout the tissues (0.1% is concentrated in the brain), and the younger the patient, the higher these indicators. Easily overcomes the BBB (blood-brain barrier between the central nervous and circulatory systems). Metabolization in the liver ranges from 80 to 95 percent, metabolites are not activated.

Cumulation does not occur, the active substance is excreted by 5% through the kidneys in an unchanged state, some of it is excreted through bile. The onset of elimination is noted after 3 hours, but the substance acts in the brain for 6 hours.

Drugs

Amphetamine

Helping the patient overcome negative manifestations in the treatment of drug addiction, Phenibut is also able to enhance the effect of nervous system stimulants on the brain. The drug itself in narcology cannot replace the same amphetamine, but if you combine these ingredients, euphoria will come much faster, and it will last twice as long.

It is this factor that encourages people to mix drugs. And with the simultaneous use of Phenibut and amphetamine, blood pressure can rise significantly.

Marijuana

Marijuana is considered a fairly easy drug, when smoked it brings a feeling of relaxation, a feeling of happiness and a desire to communicate with others. Side effects from taking THC:

  • Problems with memory and concentration;
  • Increased fatigue, causeless despondency;
  • Feelings of anxiety or panic;
  • The appearance of hallucinations, delusional states.

These side effects can be avoided when taking Phenibut. When taken at the same time, mental clarity comes and there is no “dullness” from smoking. The effect is also more pronounced.

Butyrate

Another drug with supposedly mild effects is butyrate. In small doses, it can cause a state resembling intoxication, give relaxation and lead to slight dizziness. However, when enhanced with simultaneous use of Phenibut, butyrate acts differently:

  • clearer brain function is observed;
  • behavior becomes more appropriate;
  • brain function improves;
  • fatigue and weakness are relieved.

You cannot add alcohol to such a cocktail with Phenibut. The consequences can be irreversible - simultaneous death and loss of consciousness turns into respiratory arrest and leads to death.

Hashish

When consumed, hashish gives a noticeable effect of brain activity and causes euphoria. Then a feeling of relaxation comes and your mood improves. Increasing the dose leads to impaired thinking, violent expression of emotions - laughter or crying. Smokers of this drug show empathy and a feeling of love to others.

Indications for use of Phenibut

Phenibut is prescribed in such cases as:

  • decreased brain activity;
  • fear, anxiety, causeless worry;
  • the presence of nightmares;
  • poor concentration and memory;
  • lack of emotional activity;
  • asthenic syndrome;
  • insomnia (dyssomnia);
  • somatovegetative disorder;
  • psychopathic disorders;
  • Meniere's syndrome;
  • alcohol dependence and withdrawal;
  • obsessive-compulsive neurosis;
  • osteochondrosis of the cervical and thoracic spine;
  • kinetosis (a movement disorder in which the patient feels motion sick);
  • dizziness due to vestibular dysfunction (due to infection of the body, injuries, pathologies of the circulatory system);
  • climacteric disorder;
  • urinary incontinence in a child;
  • childhood stuttering;
  • pathological hyperactivity of the baby;
  • nervous tic.

The drug is prescribed after alcohol intoxication and withdrawal from alcohol-containing drinks, especially with delirious syndrome (disorientation, clouding of consciousness, illusory hallucinations). Along with Phenibut, the patient takes detoxification medications. Quite often, the drug is used before surgery to prevent stress.

What happens if you combine Phenibut with drugs?

Drug addicts using a nootropic along with surfactants should be prepared for negative consequences:

  • intense headaches;
  • sleep disturbance;
  • unreasonable fear;
  • insurmountable anxiety;
  • frequent fainting;
  • the appearance of suicidal thoughts;
  • severe allergies;
  • exacerbation of symptoms of existing chronic diseases;
  • impulsive reactions;
  • agitation;
  • psychosis;
  • a sharp decrease in blood pressure;
  • Parkinson's disease;
  • decreased muscle tone;
  • tremor;
  • ticks;
  • decreased intellectual abilities;
  • reducing the reaction rate;
  • severe and very long-term abstinence;
  • impotence;
  • decreased sexual desire;
  • disruptions of the menstrual cycle in women;
  • gynecomastia (breast growth in men);
  • osteoporosis;
  • heart disease;
  • abdominal pain, diarrhea, constipation, drying of the mucous membranes of the oral cavity.

All this is the price for a fleeting thrill.

Medical care for a person suffering from severe withdrawal syndrome after stopping Phenibut is provided in a hospital. Treatment includes:

  • complete refusal of the provoking medication;
  • gastric lavage;
  • taking absorbents;
  • administration of laxatives;
  • infusion therapy.

With the help of a dropper, doctors remove the breakdown products of the drug from the patient's body . Due to this, negative symptoms gradually disappear.

When treating so-called phenibut addicts, special attention is paid to psychotherapy sessions . They take place in individual and group form. They are needed to increase motivation for recovery and convince the person that he needs to completely stop taking Phenibut.

Therapy for addiction to nootropics lasts relatively short - one to two months. Subsequently, the patient is advised never to resort to the help of a nootropic again.

Phenibut dosage

The drug Phenibut is taken orally (inside) in courses, depending on the indications, individual characteristics of the body, concomitant diseases and compatibility with other dosage forms. On average it is 30-45 days. The daily dosage, divided into 3 doses, for an adult varies from 0.75 grams to 1.5. In some cases, the doctor allows you to increase the norm to 2.5 g. In old age (after 60 years), the maximum dose is 0.5 grams of the active substance per dose.

Instructions for use depending on the type of pathological abnormalities:

  • For dizziness and Meniere's syndrome, a special scheme is used. In case of exacerbation of symptoms, three doses of 0.75 grams are prescribed (duration 5-7 days). After the level of symptoms has decreased, the dose is reduced to at least 0.25 g (duration is 7 days). In the final five days, the drug is taken 0.25 grams once a day.
  • For mild diseases, Phenibut is prescribed in a daily dosage of 0.5 grams, divided into 2 doses. The duration of therapy is a minimum of 5 days, a maximum of a week. Next, the patient takes 0.25 grams of tablets once a day for 7-20 days.
  • For pathologies of the circulatory system and after traumatic brain injuries, the drug is prescribed 1 tablet three times a day for 2 weeks.
  • For osteochondrosis of the thoracic or cervical spine, as well as menopausal syndrome, you need to take 1 tablet (0.25 grams) 3 times a day for 2 weeks. After this, the dosage is reduced to twice taking 1 tablet. The general course of treatment is a month, but with pronounced symptoms, the duration of treatment increases.
  • In case of alcohol withdrawal syndrome, an increased dose of the drug is required. The patient takes 1-2 tablets three times a day, and another 3 units before bedtime. After several days of treatment, the dosage is gradually reduced. As a result, it should be equal to 3 tablets per day.
  • For preventive measures (before surgery, sailing, etc.), it is recommended to take 1-2 tablets 60 minutes before the expected event.
  • If the patient shows signs of seasickness, Phenibut is combined with other medications.
  • The drug is taken after meals. If a dose was missed, the course and dosage are not changed, but continue to take the tablets in accordance with the prescribed dose.

Side effects of phenibut

Occur when the recommended dosage is exceeded or with frequent use. Most popular:

Headache and hangover effect. Weakness and depression. Psychological arousal. Confusion and nonsense. Dehydration and muscle cramps. Constipation. Gastrointestinal upset, vomiting. Breathing problems and loss of consciousness - with very large doses.

Tolerance. Characterized by a decrease in effects and the need to increase the dosage. To develop tolerance, daily intake is required for 5 days.

Addiction

It is important to observe the correct dosage and frequency of administration. The effects last for 48-72 hours, so you need to take the drug once every 2-3 days (maximum 2-3 times a week)

If there are no effects, you should take a break for 2 weeks.

Contraindications

Based on the manufacturer's instructions, Phenibut has a small list of contraindications. Admission is strictly prohibited in the following cases:

  • hypersensitivity of the body to the active or excipient substance, against which an allergic reaction occurs;
  • pregnancy period;
  • breast-feeding;
  • age category up to 2 years;
  • renal failure in the acute phase.

Relative prohibitions (use with caution):

  • erosions and ulcers in the gastrointestinal tract;
  • liver failure;
  • age from 2 to 8 years.

If there are relative contraindications, an individual (lower) dosage is prescribed. If the drug has a negative effect, it is replaced with a similar one.

special instructions

For gastrointestinal diseases, it is advisable to take the drug after meals. A dose reduction is also recommended.

When taking for more than 3 weeks, it is necessary to monitor peripheral blood parameters and liver functional activity.

During pregnancy and lactation

There is no reliable information on the safety of using Phenibut during pregnancy and lactation. Therefore, taking these tablets is not recommended for pregnant women, especially in the first trimester, as well as for young mothers who have not yet completed breastfeeding. The only exceptions can be those cases when the risk to the child is justified by the benefit to the woman’s health.

Phenibut is not recommended for use during pregnancy unless prescribed by a doctor.

In childhood

The drug can only be prescribed to children over 8 years of age. The maximum daily dose for a patient under 14 years of age should not exceed 0.75 g. The maximum single dose is 0.3 g.

For liver dysfunction

When prescribing patients with liver failure a long course of taking Phenibut tablets, it is necessary to monitor indicators of organ function. The dosage of the drug must be reduced. Otherwise, there is a risk of developing hepatotoxicity.

For liver problems, the drug is prescribed in a lower dosage.

For impaired renal function

If a person who is indicated for long-term use of Phenibut has renal failure, it is necessary to regularly monitor kidney function indicators.

Side effects

The drug causes a relatively minor number of side effects. Most often they occur in the presence of contraindications or in the early stages of a therapeutic intervention. What may be accompanied by taking Phenibut:

  • nausea;
  • increased drowsiness;
  • headache;
  • increased blood pressure;
  • excessive excitability;
  • dizziness;
  • increased anxiety, restlessness;
  • irritability.

If an allergic reaction occurs, the patient experiences swelling, hyperemia of the skin (redness), rashes, itching, burning and other allergic manifestations.

Phenibut overdose - consequences

When using high doses of nootropic, symptoms appear:

  • drowsiness and lethargy or, conversely, increased irritability and hyperactivity;
  • motor restlessness;
  • speech overexcitation;
  • insomnia;
  • headache;
  • nausea, vomiting;
  • dizziness;
  • blood pressure surges;
  • tachycardia;
  • allergy;
  • Quincke's edema.

Among the most dangerous consequences of an overdose: kidney and liver failure, internal bleeding, liver failure.

Overdose

Exceeding the dose prescribed by the doctor also leads to the development of adverse reactions, which are especially severe. In addition, the following conditions may occur:

  • a sharp drop in blood pressure;
  • fainting;
  • nausea and vomiting;
  • renal failure;
  • eosinophilia;
  • hepatic fatty degeneration;
  • kidney dysfunction.

In case of overdose, first aid must be provided. To do this, gastric lavage is performed:

  • prepare table water in the amount of a liter;
  • give the patient a drink in one gulp;
  • cause a gag reflex;
  • wait a few minutes, then repeat the procedure 2-3 more times.

Flushing is carried out immediately after dosing or the appearance of the first unpleasant symptoms. Next, you need to take absorbents - activated carbon. Toxins and the active substance are absorbed into the drug, then everything is excreted through feces.

Phenibut does not have an antidote. The drug has a low-level toxic compound, so the hepatotoxic effect occurs mainly after long-term use of excessive dosages. This leads to an increase in the concentration of eosinophils in the blood fluid of peripheral vessels. In addition, large amounts of triglycerides accumulate in the liver. It is these factors that contribute to the development of the above diseases.

Interaction

To apply the method of mutual potentiation, Phenibut is combined with other psychotropic drugs. To do this, the dosage of all drugs that are taken at the same time is reduced. Phenibut interacts well with antiparkinsonian medications, antiepileptic groups, anticonvulsants and antipsychotic drugs. Can be used along with sleeping pills and narcotic analgesics. This approach makes it possible to enhance the degree of impact of different groups of drugs, increasing the duration of action.

Compatibility of Phenibut and Phenazepam

Both drugs easily interact with each other, as they are psychotropic. Unlike Phenibut, Phenazepam is based on bromodihydrochlorophenylbenzodiazepine. In simple terms, the drug belongs to another group of psychotropics - benzodiazeline, and therefore affects the muscular and central nervous system. When they are compatible, the effectiveness of both drugs increases. It is allowed to take together and sequentially. The introduction of one of the drugs into the course of treatment is carried out gradually.

Compatibility of Phenibut and Mexidol

These are completely different drugs. Phenibut helps stimulate cognitive abilities, improve memory and brain functionality. Additionally, it has a sedative effect. Mexidol is an antioxidant that reduces the concentration of free radicals that destroy brain cells. It is used for alcohol poisoning, stress, convulsions, and nervous excitement. Therefore, both remedies are aimed at calming the nervous system. By affecting the brain differently, they enhance each other's effects. This can lead to increased lethargy and drowsiness, so during treatment it is not recommended to drive or operate a machine (due to slower reactions).

Compatibility of Phenibut and Atarax

Atarax and Phenibut belong to the anti-anxiety group, but affect the nervous system differently. The first drug eliminates alcohol syndrome, nervous overexcitation, and irritability. The second remedy fights insomnia, improves mental activity, and has a psychostimulating effect. Combining these medications gives powerful positive dynamics, so they can be prescribed simultaneously.

Compatibility of Phenibut and Fluoxetine

Fluoxetine is intended to suppress depression. The mechanism is based on an increase in the amount of serotonin in parts of the brain. This substance is responsible for a person’s mood and mental state. Phenibut is not an antidepressant, but has a calming effect on the brain, stabilizing the emotional background. Fluoxetine often causes side effects such as dizziness, insomnia, and irritability. To prevent their manifestation, Phenibut is prescribed. In addition, the nootropic enhances the effect of the antidepressant. The peculiarity is that when used together, the dosage is not reduced.

Compatibility of Phenibut and Glycine

Glycine contains an active ingredient - the amino acid glycine, which has the most gentle effect on the body. Due to this, it is often prescribed in childhood. Glycine is produced by the human body, is responsible for activating processes in the nervous system, and is a neurotransmitter. Aminophenylbutyric acid from Phenibut interacts well with glycine - the effect of the 2 drugs is enhanced. There are no adverse reactions.

Phenibut analogs

There are absolute and similar analogues of drugs. In the first case, these are drugs with the same active ingredient, in the second - drugs with the same pharmacological effect. Phenibut has many different analogues, which will be discussed further.

Which is better Phenibut or Anvifen?

Anvifen is an absolutely similar nootropic drug in relation to Phenibut, but is produced not in tablet form, but in the form of capsules (25, 50, 125, 250 mg). It is pointless to talk about which drug is better and which is worse, since they have the same effect. However, it is worth considering the pros and cons of each medication.

Phenibut:

  1. Pros:
    ● low cost; ● possible to use from 2 years of age; ● fewer contraindications than Anfiven.
  2. Cons:
    ● uncomfortable to swallow; ● produced in a single dosage: ● has a negative effect on the gastrointestinal tract.

Anvifen:

  1. Advantages:
    ● reduced negative impact on the gastrointestinal tract; ● ease of swallowing capsules; ● wide choice of dosage.
  2. Disadvantages:
    ● more contraindications; ● high cost; ● can only be used from 3 years of age.

One more negative factor can be noted for both drugs - the impossibility of dividing the tablets/capsules according to the exact dose. Tablets cannot always be broken/cut perfectly straight, and capsules cannot be separated.

Which is better - Phenibut or Noofen?

Noofen is also an absolute analogue, as it contains aminophenylbutyric acid. In order to determine which is better, you need to study their differences:

  1. Unlike Phenibut, Noofen is produced in the form of tablets, capsules, and powder. And mainly in Latvia. Phenibut is produced in 3 countries - Latvia, Russia, Belarus.
  2. The supporting cast varies. Noofen contains lactose, potato starch.
  3. Noofen is used from birth.
  4. Phenibut has more side effects.
  5. Noofen is considered more expensive in contrast to Phenibut. Its price is at least 900 rubles for 20 units. Our drug can be bought for 50-500 rubles for the same quantity (the price depends on the country of origin).

Which is better - Phenibut or Afobazole?

Afobazole refers to a nootropic drug that is based on the active ingredient febomotizole. Additionally prescribed for diseases of the cardiovascular system - heart attacks, coronary heart diseases. And also for cancer, asthma, systemic lupus erythematosus. The pharmacological action is the same, but Afobazole does not accelerate cerebral circulation, but has a slightly milder effect. Other features:

  1. Phenibut. The cost is slightly lower, the anti-anxiety effect is higher. There are more adverse reactions.
  2. Afobazol. The price is 2 times higher, but it is more easily tolerated by patients. Among the contraindications, it is worth noting lactase intolerance.

Thus, if a person has poor blood circulation, there is no deficiency of lactase enzymes, and also needs to achieve high anti-anxiety effectiveness, then it is better to purchase Phenibut.

Which is better - Phenibut or Grandaxin?

Grandaxin belongs to the group of benzodiazepine-based tranquilizers. The drug is used for alcohol and drug withdrawal, moderate depression, anxiety and nervous system disorders. It is distinguished by the absence of a sedative effect, therefore, on the contrary, it invigorates and excites, which means that the anti-anxiety effect is achieved slowly. In addition, the drug has a large list of adverse reactions and contraindications (additionally - atherosclerosis, respiratory failure, epilepsy, impaired blood supply to the brain).

Which is better - Phenibut or Pantogam?

Pantogam and Phenibut have the same mechanism of action, as they belong to the group of nootropic drugs, but the indications for use differ slightly. Pantogam is recommended for decreased performance, schizophrenia, senile dementia, and impaired urination. But there are also general indications: traumatic brain injuries, circulatory disorders in the brain, pathologies of the circulatory system. It also has a calming effect, but very weakly. It is impossible to completely get rid of anxiety, so preference should be given to Phenibut. The cost of Pantogam is much higher. The instructions for use contain a small list of adverse reactions; the drug can be taken from early childhood (in the form of syrup), so Pantogam is recommended for children.

Which is better - Phenibut or Adaptol?

Adaptol is a daytime tranquilizer, as it does not promote sleep. The composition contains the active substance tetramethyltetraazabecyclooctanedione, that is, mebicar, and therefore has cerebroprotective and antioxidant properties. Phenibut and Adaptol are similar in some general indications, but there are still differences:

  1. Phenibut is a nootropic, Adaptol is an anxiolytic, so they affect the body differently.
  2. The first drug has a wider spectrum of action (anxiety, insomnia, consequences of trauma, impaired concentration and memory, urinary incontinence, stuttering, tickpsychopathy, somovegetative disorders), the second - only ischemic heart pain, neurosis, alcohol and nicotine addiction.
  3. Phenibut is produced in 3 countries, so you can buy tablets from a budget option.
  4. Adaptol has a smaller list of side effects, but Phenibut has a stronger and faster effect.

Which is better - Phenibut or Teraligen?

If Phenibut belongs to the nootropic group, then Teraligen belongs to the neuroleptic group, therefore it is used for mental diseases, allergies, vomiting, etc. Both drugs have a common effect: they eliminate nervous tension and relieve muscle spasms. Stabilizes sleep, neutralizes anxiety and calms. Differences:

  1. Phenibut is a nootropic and at the same time an anxiolytic, while Teraligen is an antihistamine and an antipsychotypic drug, and therefore has a narrower range of applications.
  2. Teraligen has a more powerful anti-anxiety effect (which is why it is used for chronic depression), but Phenibut has a milder effect.
  3. The first drug has more contraindications and side effects.

Which is better - Phenibut or Tenoten?

Both drugs belong to the group of nootropics and anti-anxiety drugs, but their mechanism of action is different. Tenoten is based on antibodies to the brain-specific protein S-100, therefore it accelerates metabolism and increases energy reserves in brain neurons. Antibodies, when combined with proteins, change their properties, which improves the transmission of nerve impulses. This leads to increased resistance of the nervous system to hypoxia (oxygen starvation does not occur). This is especially important for affected areas.

The peculiarity of the drug is its ability to have both a sedative and stimulating effect, depending on the pathological abnormality. Thus, Tenoten is used for increased excitability and irritability, and Phenibut for fears, nervousness, and anxiety. It is impossible to say unequivocally which medication is better, since their prescription is based on the causes of pathologies, accompanying symptoms and features of the course of the disease.

What is better - Phenibut or Phenotropil?

Phenotropil is a nootropic drug with the active ingredient of the same name. The action is aimed at improving concentration and attention, memory, increasing energy reserves, like Phenibut, so the drugs improve the functionality of the brain. However, Phenotropil does not provide a sedative effect, does not fight insomnia, but, on the contrary, leads to excitability and activation. Consequently, the indications for the products are slightly different:

  1. Phenibut: tic, seizures, insomnia, anxiety, etc.
  2. Phenotropil: neurosis in which psychomotor activity is impaired, prolonged depression, convulsions, diseases of the circulatory system.

Based on the above, Phenibut and Phenotropil have one thing in common - improving brain activity. When prescribing, the doctor is guided by the cause of the patient’s condition.

Does Phenibut lower or increase blood pressure?

Phenibut is a drug belonging to the group of nootropics, which is a moderate tranquilizer (anxiolytic). The drug activates the brain and normalizes blood circulation in the central nervous system.

The drug is prescribed for urinary incontinence, neurotic, anxious and asthenic conditions. The medicine is also indicated for Meniere's disease, tics, stuttering, insomnia, neuroses, high blood pressure, alcohol or drug withdrawal, etc.

Composition, release form, dosage

Phenibut is available in the form of powder and tablets intended for internal use. The active ingredient of the product is aminophenylbutyric acid. Auxiliary components of the drug:

  1. stearic calcium;
  2. lactose;
  3. low molecular weight polyvinylpyrrolidone;
  4. starch.

Phenibut powders, used for high blood pressure, are available in 100 mg doses, and 250 mg tablets.

Reviews from doctors and patients indicate that it is best to buy Phenibut from a Latvian manufacturer. Also, good quality of drugs was noted from such companies as MIR-Pharm and Ozon.

Therapeutic effect

The active ingredient of the drug - aminophenylbutyric acid - is a derivative of phenylethylamine and gamma-aminobutyric acid - GABA. This is a brain metabolite that is used by the structures of the central nervous system for the metabolic process and the normal functioning of brain cells.

GABA is a nootropic, that is, it improves memory, mental speed and thought processes. Phenylethylamine, which is part of Phenibut, is a tranquilizer. It improves performance and eliminates anxiety.

Therefore, if high blood pressure is caused by constant stress, emotional or physical stress, then Phenibut will be the best choice. After all, it quickly lowers blood pressure, eliminating anxiety and anxiety.

The drug has the following therapeutic effects:

  • eliminating fear, anxiety, tension, worry;
  • activation of mental performance;
  • getting rid of insomnia;
  • improving reaction speed, attention and memory;
  • reducing the severity of movements and speech disorders;
  • activation of cerebral circulation (vascular resistance decreases and blood flow speed accelerates);
  • reduction of asthenic manifestations.

In addition, Phenibut eliminates signs of VSD (emotional instability, headache, irritability, etc.) and increases motivation and interest in various activities.

The drug also has a slight anticonvulsant effect and reduces the inhibitory effect of alcohol on the central nervous system, as evidenced by reviews. It is noteworthy that Phenibut enhances the effectiveness of antipsychotics, narcotics and sedatives.

In addition, when using the drug in patients over 65 years of age, relaxation and lethargy do not occur. On the contrary, it stimulates vigorous activity.

Indications and instructions for use

In addition to neuroses, anxiety, asthenic conditions and insomnia, Phenibut is prescribed for Meyer's disease and other pathologies of the vestibular system caused by vascular disorders and injuries.

Phenibut for children

Phenibut has a low level of toxicity and a mild effect, therefore it is prescribed to children starting at the age of 8 years. However, there are exceptions when the drug is taken from 2 years of age. In this case, it is necessary to purchase not the tablet form, but the powder form, which is prepared by pharmacists directly in the formulation department of any pharmacy. This is convenient because the drug can be given in any low dosage. Based on the instructions for use, from 8 to 14 years old the recommended daily dose is 0.75 grams, divided into 3 doses. In particularly difficult situations, the norm may be increased to 100 mg.

Indications for children:

  • nervous tic;
  • stuttering;
  • urinary incontinence;
  • neurosis, anxiety disorders.

To achieve positive dynamics during therapy, it is recommended to additionally take other groups of drugs and use special techniques, since Phenibut enhances the effect of other drugs.

In childhood, long-term use (more than a month) is prohibited, because it is possible to develop psychological dependence on the tablets (powder). It is not advisable to give the drug to newborns and children under 2 years of age. This is due to the fact that the active substance has a multidirectional effect, so the body’s reaction can be negative.

Instructions on how to take Phenibut

In order to obtain a noticeable effect and long-lasting action, the drug must be taken in courses of 2-3 or 4-6 weeks with a mandatory break of at least 2 weeks. To minimize the negative impact on housing and communal services, tablets are taken after meals.

Depending on age, the following is prescribed:

  • children from 3 to 8 years old: 50-100 mg 3 times a day;
  • children from 8 to 14 years old: 250 mg 3 times a day;
  • children over 14 years of age and adults 250-500 mg 3 times a day.

Phenibut dosage varies depending on the age and condition of the patient

According to the instructions, the maximum dose that an adult can take at a time without harm to health is 750 mg. It is also recommended as a daily norm, but according to the instructions of the attending physician, it can decrease or increase.

For example, for moderate fatigue, irritability and lack of motivation during parental leave, the psychotherapist recommends taking one tablet in the morning and evening for a month, which is 500 mg per day and 60 tablets per course in total. Such a gentle dosage helps to “wake up”, increase interest in life, but at the same time not become addicted to phenibut.

Can children take phenibut?

Although the instructions for the drug directly indicate that it can be given to children from 3 years of age, many parents are afraid to do this even with the clear instructions of a doctor. Phenibut is perceived by them as a potent psychotropic substance and almost a drug. In fact, it is practically harmless and can provide real help in many painful conditions.

Phenibut is approved for use by children over 3 years of age

The famous children's pediatrician Komarovsky, who is trusted by the majority of mothers in Russia and Ukraine, also agrees with his colleagues in the safety of phenibut for children. He explains that the drug belongs to the group of nootropics and improves metabolism in brain cells, while having a calming effect. Therefore, so that when you stop taking the drug, increased excitability does not appear, and it does not seem that the child is “addicted to pills,” you can give other sedatives, at least on a plant basis.

How much can you take phenibut

If you ignore the instructions and take the nootropic for more than a month and a half in a row, then when you stop using it, you may encounter a “withdrawal syndrome.” It manifests itself in a sharp psychological or physiological deterioration in well-being, the seeming inability to function normally without taking pills. In particularly difficult cases, the condition after stopping Phenibut may become even worse than before starting to take it.

Compatibility of Phenibut and alcohol

The drug is prescribed by narcologists to eliminate symptoms in the following cases:

  • alcohol addiction;
  • preliminary state;
  • delirium;
  • alcohol withdrawal.

Based on this, many people mistakenly believe that Phenibut is compatible with alcohol-containing drinks (there are no direct indications of a prohibition in the instructions of the certified drug). This is fundamentally not true, because the active substance acts as follows:

  • The drug has a sedative effect, so when drinking alcohol, intoxication increases many times and has a pathological form. Against this background, powerful intoxication of the body occurs and instant addiction to the drug occurs, which is fraught with subsequent addiction (many alcohol addicts like the quick effect of intoxication).
  • Aminophenylbutyric acid and alcohol are similar in their mechanism of action on metabolism, so competition arises between them. To put it simply, ethanol and the active substance of the drug seem to compete with each other, suppressing and changing each other’s effects. As a result, the desired effect is not achieved, but side reactions occur, which is fraught with life-threatening complications.

Reviews from men and doctors' opinions

On men's forums you can find various reviews about the effect of Phenibut on the body and potency. For some men, the drug served as a libido stimulant, for others it was a good sleeping pill, and still others did not feel any changes. There are also complaints about a sharp decline in sexual desire, even to the point of impotence (as a consequence of a course of treatment).

Many people praise Phenibut as an effective remedy for one-time calming during severe stress. After about half an hour, the brain abstracts from events that interfere with concentration and constructive thinking. Most men taking the drug against the background of psychogenic impotence were satisfied with its effect.

Doctors do not advise increasing libido with the help of a prescription nootropic, recommending tincture of ginseng, lemongrass or aralia for these purposes. Natural Phenibut is Rhodiola rosea.

Phenibut and potency are not directly related. This drug is primarily a medicine that a healthy person does not need. If there is chronic stress or depression that interferes with normal sex life, then a nootropic will help eliminate them. It should not be used as a stimulating dietary supplement - the effect may be the opposite.

Prescription of the drug during pregnancy

The nootropic Phenibut is prohibited for use during pregnancy and lactation. This is especially true in the first trimester, when the fetus is just beginning to form. During this period, the main systems and organs are formed. Due to the fact that no studies have yet been conducted on the effect of GABA derivatives on the embryo, the medication is not prescribed until 3 months of pregnancy.

In the 2nd and 3rd trimester, Phenibut can be prescribed, but only in a situation where the likely benefit outweighs the potential harm to the unborn baby. In this case, the dosage and duration of the course are determined primarily by the attending doctor. In this case, medical supervision is required.

During breastfeeding, the drug is prescribed with great caution, since there is no official data on the penetration of the active substance into breast milk. If the intake is recommended by another specialist, then you will have to give up lactation and transfer the baby to artificial feeding.

Hallucinations from nootropic development

Phenibut by itself cannot cause hallucinations, so you should not believe people who claim this. However, if it is combined with psychoactive substances and drugs, the consequences can be unpredictable.

The addict begins to hear voices with which he talks. But, it should be noted, this is only possible when taking very high doses, many times higher than therapeutic ones.

Manufacturer

Phenibut is produced in 3 countries by the following pharmaceutical companies:

  • Russia: Ozon LLC, Organika OJSC, Moscow Endocrine Federal State Unitary Enterprise, Usolye-Sibirsky Chemical Physics Complex.
  • Latvia: JSC "Olainfarm" (Olainfarm).
  • Belarus: Belmedpreparaty.

The prescription of the drug Phenibut is carried out by the treating specialist after a comprehensive examination of the patient. Only the doctor determines the dosage and duration of the course based on the results of diagnostic measures. During the therapeutic course, the patient's condition is monitored. Self-medication is strictly prohibited, as life-threatening consequences may occur.

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